%0 Journal Article
%T Study of Recombinant Stem Cell Factor<br>重组人干细胞因子的研究
%A WU Jun
%A GONG Xin
%A CHANG Shao-Hong
%A ZHAO Zhi-Hu
%A ZUO Cong-Lin
%A MA Qing-Jun
%A <br>吴军
%A 巩新
%A 唱韶红
%A 赵志虎
%A 左从林
%A 马清钧
%J 生物工程学报
%D 2003
%I 
%X Stem cell factor is an important hematopoietic growth factor. In this study, the human stem cell factor was produced by recombinant E.coli,and the structure and biological activity of the recombinant stem cell factor(rhSCF) was studied.It was indicated that the rhSCF was a uncovalent dimer in phosphate buffer,and had the correct mass spectra, mass peptides spectra, composition of amino acid, N-terminal sequernce,C-terminal sequence and intrachain disulfide linkages, rhSCF alone or synergy with rhG-CSF could mobilze hematopoietic progenitors to blood in monkey.
%K stem cell factor
%K gene expression
%K hematopietic growth factor<br>干细胞因子，
%K 基因表达，
%K 造血生长因子
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=F440DF24AA2CD6DB&yid=D43C4A19B2EE3C0A&vid=2A8D03AD8076A2E3&iid=B31275AF3241DB2D&sid=6CDD207A90CE1EEC&eid=F20A770D14436F7C&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=2&reference_num=12