%0 Journal Article
%T Effect of acetic acid, furfural and 5-hydroxymethylfurfural on production of 2,3-butanediol by Klebsiella oxytoca<br>乙酸、糠醛和5-羟甲基糠醛对产酸克雷伯氏菌发酵生产2,3-丁二醇的影响
%A 吴晶
%A 程可可
%A 李文英
%A 冯杰
%A 张建安
%J 生物工程学报
%D 2013
%I 
%X To get the tolerability and consumption of Klebsiella oxytoca on major inhibitors in lignocelluloses hydrolysate, we studied the effect of acetic acid, furfural and 5-hydroxymethylfurfural on production of 2,3-butanediol by Klebsiella oxytoca. The metabolites of furfural and 5-hydroxymethylfurfural were measured. The results show that when acetic acid, furfural and 5-hydroxymethylfurfural was individually added, tolerance threshold for Klebsiella oxytoca was 30?g/L, 4 g/L and 5 g/L, respectively. Acetic acid was likely used as substrate to produce 2,3-butanediol. The yield of 2,3-butanediol increased when acetic acid concentration was lower than 30 g/L. In the fermentation, more than 70% 5-hydroxymethylfurfural was converted to 2,5-furandimethanol. All furfural and the rest of 5-hydroxymethylfurfural were metabolized by Klebsiella oxytoca. It showed that in the detoxification process of 2,3-butanediol production using lignocelluloses hydrolysate, furfural should be given priority to remove and a certain concentration of acetic acid is not need to removal.
%K Klebsiella oxytoca
%K 2
%K 3-butanediol
%K acetic acid
%K furfural
%K 5-hydroxymethylfurfural
%K inhibitor<br>产酸克雷伯氏菌，2
%K 3-丁二醇，乙酸，糠醛，5-羟甲基糠醛，抑制物
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=2C0F2EE71B46795FAB045305A7850502&yid=FF7AA908D58E97FA&vid=771469D9D58C34FF&iid=38B194292C032A66&sid=406BF8ED3BCE1927&eid=FA88DCCE84EA0A56&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=0