%0 Journal Article
%T EFFECT OF PHENYLHYDRAZINE ON STRUCTURE AND FUNCTION OF ERYTHROCYTE MEMBRANES<br>苯肼对红细胞膜结构和功能的影响
%A Hu Chuan Xu Hong Zhou Hanqing Zhanh Zhihonh
%A <br>胡船
%A 许红
%A 周汉清
%A 张志鸿
%J 生物物理学报
%D 1992
%I 
%X The membrane-Hb interaction was modified by treating intact erythrocytes with phenylhydrazine. The effect of the modification on structure and function of erythrocyte membrane was studied by measuring osmotic hemolytic process, fluorescent quenching, and anion transport. The fast process (K1) of osmotic hemolysis was affected at phenylhydrazine concentration >0.01 mM. This means that the membrane fluidity is decreased. The binding of Hb to the membrane was increased rapidly at phenylhydnazine concentration > 0.1 mM. Furthermore, we observed that the anion transport across erythrocyte membrane was increased due to change of membrane structure.
%K Erythrocyte membranes
%K phenylhydrazine
%K the rate of osmotic hemolysis
%K fluorescent quenching
%K anion transport<br>红细胞膜
%K 苯肼
%K 结构
%K 功能
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=4006DFDFD8B7EBCE7A626BEF3051659C&yid=F53A2717BDB04D52&vid=5D311CA918CA9A03&iid=38B194292C032A66&sid=B7B25E832E7F23D8&eid=B99A53AADE50D922&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=0&reference_num=5