%0 Journal Article
%T Structure Kinetic Model of Maackia amurensis Cells in Suspension Culture<br>怀槐细胞悬浮培养的结构化动力学模型
%A LUO Kai
%A ZHA Xue-Qiang
%A LUO Jian-Ping
%A <br>罗凯
%A 查学强
%A 罗建平
%J 生物工程学报
%D 2007
%I 
%X A structure kinetic model was established for describing the relationship among cell growth, genistein formation and substrate utilization in suspension culture of Maackia amurensis. In this model, sucrose uptake, structure components production, intermediate matter changes, cell respiration loss and secondary metabolite (genistein) production were all predicted. The parameter sensitivity test was indicated that intermediate matter self-catalysis rate constant (k_ b1 ), structure component synthesis rate constant (k_ b2 ) and secondary metabolite synthesis rate constant (k_p) were the most sensitive parameters for this model. If k_ b1 , k_ b2 or k_p are changed by 10%, the range of the aim function value would be changed by 12.8%, 4.61% and 2.54%, respectively. Adjustment of the other parameters only aroused a change of less than 0.5% in the aim function value. The predicted values were in good agreement with those obtained experimentally.
%K Maackia amurensis
%K suspension culture
%K structure model
%K genistein<br>怀槐
%K 悬浮培养
%K 结构模型
%K 染料木素
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=3823EB853993C751&yid=A732AF04DDA03BB3&vid=EA389574707BDED3&iid=E158A972A605785F&sid=E934BC2766053B28&eid=8DDBA6455F2E3ECF&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=0&reference_num=12