%0 Journal Article
%T CHAOS IN WAVELET COMPONENTS OF AUDITORY EVOKED EEG FOR INFANTILE SPASMS<br>听觉诱发脑电小波分量的混沌研究——婴儿痉挛症认知功能障碍的机制探讨
%A TAO Hua-ying
%A TIAN Xin
%A CHEN De-mei
%A <br>陶华英
%A 田心
%A 陈德美
%J 生物物理学报
%D 2003
%I 
%X Infantile spasms is a special form of epilepsy, which occurs during infancy. The pathogenesis of infantile spasms has not been known yet. However, when infantile spasms is associated with structural damage to the brain, it is difficult to completely control the seizures and intellectual, and cognitive impairment is very likely to be present. One of current hypothesis about the pathogenesis of IS is that brainstem is the responsible structure of IS, the reason why most IS suffers cognition impairment is still unknown. The pathogenesis as well as the accompanied cognition impairment of IS has been approached from the view of information science, with the help of the wavelet and chaos theory. IS and normal groups' evoked EEGs were recorded with the auditory stimulation. After pre-process and Maxihat wavelet transform were performed, the EEG signal was decomposed into different components in 7 scales, and their correlation dimensions (Dc) were calculated. The results show that the normal group's Dc in three scale is significantly lower than that in the IS, in other scales no significant difference has been found. It is known that the freedom degree of brain activity becomes lower and the coupling among the components in brainstem reinforces when Dc declining. In the IS group, the pathway of information in brain stem is in bad condition. This makes the coupling more difficult. So Dc in the IS shows higher than that in the normal in three scales. Meanwhile, the 3,4 scales are in the high frequency range (32~64 Hz), which is relative to the brain cognition function. From informatics it is may be explained why IS infants always accompany with cognition impairment. The conclusion can be drawn that the abnormal EEG signal in gamma frequency in IS may cause the cognition impairment in IS.
%K Infantile
%K spasms (IS)
%K Auditory
%K brain-stem
%K evoked
%K EEG
%K Cognition
%K impairment
%K Wavelet
%K transform
%K Correlation
%K dimension (Dc)<br>听觉
%K 脑电小波
%K 混沌
%K 婴儿痉挛症
%K 认知功能障碍
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=4036A9EE71F9D110&yid=D43C4A19B2EE3C0A&vid=2A8D03AD8076A2E3&iid=38B194292C032A66&sid=E3094127AA4ABC1A&eid=4AD4BA66429F5627&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=0&reference_num=17