%0 Journal Article %T A KNOWLEDGE-BASED PROTEIN MODELING SYSTEM AND ITS EVALUATION
基于结构比较的蛋白质模建系统及其评估 %A Ding Dafu %A Tang Haixu %A Zhang Baohong %A
丁达夫 %A 汤海旭 %A 张保红 %J 生物物理学报 %D 1995 %I %X Based on previous elaborate researches on knowledge-based protein modeling, a new software of modeling a protein of known sequence but unknown structure from structures of homologous proteins is integrated. It consists of two major components, the backbone modeling and side-chain placement, totally including seven modules. The restilts of 11 families of protein modeling show that the system is of the advantages of high pration, less CPU-time and full automation. This paper also predictively models other four proteins, whose structures are unknown nowadays (a neutral phospholipase A2, a lignad for CD40, mouse mast cell protease and human interleukin-13). %K Knowledge-based protein modelling Backbone modelling Evaluation
蛋白 %K 理论生物物理 %K 蛋白质同源模建 %K 评估 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=8760C2861E15B2FE5E3DC1FAD8888B0C&yid=BBCD5003575B2B5F&vid=708DD6B15D2464E8&iid=38B194292C032A66&sid=1FF3CD54EFC256A1&eid=CB3428B1EFB1C133&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=4&reference_num=8