%0 Journal Article %T Construction and Expression of Coexpression Plasmid of Carcinoembryonic Antigen and Newcastle Disease virus HN Gene
人癌胚抗原与新城疫病毒HN基因共表达载体的构建及表达 %A WEI Lin %A DAI Jian-Xin %A SUN Shu-Han %A
魏林 %A 戴建新 %A 孙树汉 %J 生物工程学报 %D 2000 %I %X The eukaryotic expression plasmid (pcDNA3-CEA)containing with the gene coding for the Carcinoembryonic antigen(CEA) had been gotten with RT-PCR and gene recombination techniques. Using enzymolysis, ligation and other techniques, an eukaryotic coexpression plasmid(pcDNA3-CEA/HN)containing two expression unites of CEA and Newcastle disease virus HN gene that may have the function of immunoenhancement had been constructed. The plasmid will lay a foundation for further researching CEA nucleiotide vaccine, adjuvant and their effect of special antitumor immune. %K Carcinoembryonic antigen %K newcastle disease virus HN gene %K coexpression plasmid
癌胚抗原 %K 新城疫病毒HN基因 %K 共表达质粒 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=C7629791F9A2483B&yid=9806D0D4EAA9BED3&vid=7801E6FC5AE9020C&iid=94C357A881DFC066&sid=9A596D09E9486F3E&eid=0636354D8CF77519&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=2&reference_num=7