%0 Journal Article
%T Bioactive Compounds from Marine Sponges and Cell Culture of Marine Sponges<br>海绵生物活性物质及海绵细胞离体培养
%A ZHANG Xiao-Ying- ZHAO Quan-Yu
%A XUE Song
%A ZHANG Wei
%A <br>张骁英
%A 赵权宇
%A 薛松
%A 张卫
%J 生物工程学报
%D 2002
%I 
%X Presented a survey of bioactive compounds discovered from marine sponges in the recent five years, including the classes, distribution and their potential pharmaceutical uses. In particular, the compounds with antitumor, antivirus and antibacteria activity were discussed with their originating marine sponge species. Whereas the "Supply Problems" were identified to hinder the clinical tests and commercial applications of most of the sponge bioactive compounds. In vitro cell culture of marine sponges is one of the most promising approaches to solve this problem. The state-of-the art of marine sponge cell culture and the challenging areas were discussed. A brief summary of the R&D status was also given on the bioactive compounds from marine sponges in Chinese oceans. It is crucial to invest more efforts on studying marine sponges and their bioactive compounds in our country in order to develop new marine drugs of independent intellectual property.
%K marine sponge
%K bioactive compounds
%K \%in vitro\% cell culture<br>海绵
%K 生物活性物质
%K 细胞离体培养
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=A66E90C274451689E69F6F0291467824&aid=7A3F1FC645947D93&yid=C3ACC247184A22C1&vid=13553B2D12F347E8&iid=CA4FD0336C81A37A&sid=F3090AE9B60B7ED1&eid=23CCDDCD68FFCC2F&journal_id=1000-3061&journal_name=生物工程学报&referenced_num=12&reference_num=42