%0 Journal Article
%T Loss of c-Met Disrupts Gene Expression Program Required for G2/M Progression during Liver Regeneration in Mice
%A Valentina M. Factor
%A Daekwan Seo
%A Tsuyoshi Ishikawa
%A Pal Kaposi-Novak
%A Jens U. Marquardt
%A Jesper B. Andersen
%A Elizabeth A. Conner
%A Snorri S. Thorgeirsson
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0012739
%X Previous work has established that HGF/c-Met signaling plays a pivotal role in regulating the onset of S phase following partial hepatectomy (PH). In this study, we used Metfl/fl;Alb-Cre+/£¿ conditional knockout mice to determine the effects of c-Met dysfunction in hepatocytes on kinetics of liver regeneration.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0012739