%0 Journal Article %T CREB Inhibits AP-2¦Á Expression to Regulate the Malignant Phenotype of Melanoma %A Vladislava O. Melnikova %A Andrey S. Dobroff %A Maya Zigler %A Gabriel J. Villares %A Russell R. Braeuer %A Hua Wang %A Li Huang %A Menashe Bar-Eli %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0012452 %X The loss of AP-2¦Á and increased activity of cAMP-responsive element binding (CREB) protein are two hallmarks of malignant progression of cutaneous melanoma. However, the molecular mechanism responsible for the loss of AP-2¦Á during melanoma progression remains unknown. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0012452