%0 Journal Article
%T New Function for an Old Enzyme: NEP Deficient Mice Develop Late-Onset Obesity
%A Matthias Becker
%A Wolf-Eberhard Siems
%A Reinhart Kluge
%A Florian Gembardt
%A Heinz-Peter Schultheiss
%A Michael Schirner
%A Thomas Walther
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0012793
%X According to the World Health Organization (WHO) there is a pandemic of obesity with approximately 300 million people being obese. Typically, human obesity has a polygenetic causation. Neutral endopeptidase (NEP), also known as neprilysin, is considered to be one of the key enzymes in the metabolism of many active peptide hormones.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0012793