%0 Journal Article
%T MODEL ANALYSIS OF GRADED DENDRITIC SPIKESIN HIPPOCAMPAL CA1 PYRAMIDAL CELLS
海马CA1区锥体细胞树突分级峰电位的模型分析
%A SHEN Gong-yu
%A
沈公羽
%J 生物物理学报
%D 2000
%I
%X Neurons in the brain are endowed with complex information processing functions by their complex dendritic tree structures and voltage-gated ion channels. The neuronal information integration properties were investigated by means of branch morphological model and voltage-gated ion channel kinetic models, including the transient K channel. The results show that the voltage level of distal dendritic spikes is graded in a large range of input intensity, the initiation site of action potential can shift along the apical dendrite, and the amplitude of the back-propagating spike can decrease abruptly when it reaches the distal dendrite.
%K Neuronal model
%K Dendrite
%K Graded dendritic spike
%K Transient potassium channel
神经元模型
%K 树突
%K 分级峰电位
%K A型钾通道
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=D3036B545DE6A67DCE3FA2F178D49921&yid=9806D0D4EAA9BED3&vid=7801E6FC5AE9020C&iid=38B194292C032A66&sid=20ADD38F841C6A4B&eid=E49BED2EA9A8956B&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=0&reference_num=2