%0 Journal Article %T STUDY OF THE PRODUCTION OF HYDROXYL RADICAL BY STIMULATED ALVEOLAR MACROPHAGES OF RAT WITH ESR SPECTROSCOPY
ESR检测大鼠肺巨噬细胞释放的活性氧自由基 %A Hu Lianping %A Sun Cunpu %A Cong Jianbo %A Gong Yifen %A Wu Ke %A Wu Dechang %A
胡连平 %A 孙存普 %A 丛建波 %A 龚治芬 %A 吴可 %A 吴德昌 %J 生物化学与生物物理进展 %D 1990 %I %X The characterizations of oxygen radicals released from alveolar macrophages (AM) of rats and related measurement conditions were observed with the technique of ESR in this experiment. The results were summarized as follows.1. Of PMA, BCG, ConA and cis-platinum, the first two stimulated AM to produce hydroxyl radical.2. AM stimulated by different agents had different kinetics of the release of the hydroxyl radical. The release peak from AM appeared at min. two after stimulating AM with PMA, with BCG the release peak delayed obviously.3. 5×107AM/ml proved the fit concentration for trapping the signal of the hydroxyl radical from AM in this experiment. 4. There was a great influence of DETAPAC or EDTA on the intension of the signal. %K macrophage %K free radiclas
巨噬细胞 %K 自由基 %U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=BC64BF105951C13A70499791E1DA6FA4&aid=D76502D9B4CF4949197A3A54FFB09BE7&yid=8D39DA2CB9F38FD0&vid=BCA2697F357F2001&iid=E158A972A605785F&sid=11CEECA6DA9E4AC5&eid=F50A8B5513721E1C&journal_id=1000-3282&journal_name=生物化学与生物物理进展&referenced_num=4&reference_num=0