%0 Journal Article
%T SELF-ASSEMBLING BILAYER LIPID MEMBRANES ON SOLID SUPPORT<br>固体支撑的自组装的双层类脂膜
%A H Ti TIEN
%A Z SALAMON
%A <br>田心棣
%A Z. SALAMON
%J 生物化学与生物物理进展
%D 1990
%I 
%X Solid supported bilayer lipid membranes (S-BLM) that posses some properties similar to those of conventional BLMs can be self-assembled on a freshly cleaved metal wire by a twostep procedure: 1. The tip of a Teflon-coated platinum wire, while immersed in a lipid solution, is cut off with a scalpel; 2. The new tip of the wire, having become coated with lipid solution, is transferred into 0.1 mol/l KCl. After a few minutes, a stable lipid bilayer forms spontaneously on the tip of wire, as verified by electrical measurements. This paper reports an application of such a supported BLM (S-BLM) in the detection of Pb2+ ions. The S-BLM is liquidcrystalline in structure, which makes it amenable to modification for basic studies, as well as for technological applications such as biobensors and molecular electronic devices.
%K BLM (bilayer lipid membrane)
%K S-BLM (solid supported bilayer lipid membrane) biosensors
%K molecular electronic devices<br>BLM（双层类脂膜）
%K S-BLM（固体支撑的双层类脂膜）
%K 生物传感器
%K 分子电子器件
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=BC64BF105951C13A70499791E1DA6FA4&aid=2659D3CE2F3C2019E4D1FA743C76CCDC&yid=8D39DA2CB9F38FD0&vid=BCA2697F357F2001&iid=94C357A881DFC066&sid=3356A7630A93A219&eid=8C27CCA578E52082&journal_id=1000-3282&journal_name=生物化学与生物物理进展&referenced_num=1&reference_num=0