%0 Journal Article
%T A New Encoding Scheme for Protein Structure And Its Application
一种新的蛋白质结构编码方法及其应用
%A CHEN Shuang-ping
%A ZHENG Hao-ran
%A Ning Yan
%A WANG Xu-fa
%A
陈双平
%A 郑浩然
%A 宁岩
%A 王煦法
%J 生物物理学报
%D 2005
%I
%X Based on the results of visualized clustering of tetra-peptide conformations in native protein structures, a new encoding scheme that converts 3D structure of proteins into character strings is advanced. Thus, the problem of seeking motifs of protein structures can be solved in a character sequence space. The reliability and accuracy of the scheme are validated based on two algorithms that are deve- loped for querying and discovering motifs. The concept of entropy is introduced to explore the relations between amino acid sequence and structure of proteins, and hundreds of sequence-structure motifs are obtained. Compared with results of other methods, the scheme is more accurate and explicable.
%K Encoding scheme
%K Entropy
%K Sequence-structure motif
%K Tetra-peptide conformational space
编码
%K 熵
%K 序列-结构模式
%K 四肽构象空间
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=CBD94D9EBBA6CB7A&yid=2DD7160C83D0ACED&vid=659D3B06EBF534A7&iid=0B39A22176CE99FB&sid=DDD31293A7C7D057&eid=2B5DE8A23DCEED39&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=0&reference_num=19