%0 Journal Article
%T CODON USAGE IN GENES CODING FOR PROTEINS WITH DIFFERENT TERTIARY STRUCTURES
不同结构的蛋白编码基因的密码子偏性研究
%A GU Wan-jun
%A MA Jian-min
%A ZHOU Tong
%A SUN Xiao
%A LU Zu-hong
%A
顾万君
%A 马建民
%A 周童
%A 孙啸
%A 陆祖宏
%J 生物物理学报
%D 2002
%I
%X Based on gene codon usage distance 75 genes coding for proteins with two different fingerprints were clustered, to analyze the relationship between gene codon usage and protein tertiary structure. It was found that 75 genes coding for proteins with different tertiary structure can be clearly classified into two groups according to the difference of codon usage bias, which suggests that codon usage is lighly corrclated to protein tertiary structure. The relationship between codon usage and protein tertiary structure is firstly found in the research of codon usage, which proves that gene sequence contains protein tertiary structure information.
%K Codon usage
%K Protein tertiary structure
%K Cluster analysis
%K mRNA
蛋白编码基因
%K 偏性
%K 密码子
%K 蛋白质三级结构
%K 聚类分析
%K mRNA
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=51053C48B19DAC90&yid=C3ACC247184A22C1&vid=13553B2D12F347E8&iid=CA4FD0336C81A37A&sid=35FC3610259C2B32&eid=7AA74D31F1FF2DCE&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=18&reference_num=16