%0 Journal Article
%T EFFECT OF Pb2+ ON THE H-CURRENT ELICITED IN THE ACUTELY DISSOCIATED HIPPOCAMPUS CELL<br>铅对大鼠海马神经细胞H-电流特性的影响
%A XIONG Qiao-jie
%A GE Shao-yu
%A HE Shui-jin
%A GU Yan
%A RUAN Di-yun
%A <br>熊巧婕
%A 葛少宇
%A 何水金
%A 谷岩
%A 阮迪云
%J 生物物理学报
%D 2002
%I 
%X Effect of Pb2+ on hyperpolarization-activated current (H-current) of rat hippocamal cell was studied with whole cell patch clamp technique. The results demonstrated: Pb2+ suppressed the expression of H-current, decreased the voltage sensitivity and increased the activation voltage. Suppression of the expression and change of the voltage-sensitivity of H-current may be one pathway by which Pb2+ expressed its toxicity.
%K Pb2+
%K Hippocampal cell
%K Whole cell patch clamp
%K H-current<br>铅
%K 大鼠
%K 海马神经细胞
%K H－电流特性
%K 全细胞膜片钳技术
%U http://www.alljournals.cn/get_abstract_url.aspx?pcid=90BA3D13E7F3BC869AC96FB3DA594E3FE34FBF7B8BC0E591&jid=E0C9D9BBED813D6674AC13E942EAC86D&aid=D619A1ED26BBA36C&yid=C3ACC247184A22C1&vid=13553B2D12F347E8&iid=0B39A22176CE99FB&sid=2BA123C6EB9D54C2&eid=1E41DF9426604740&journal_id=1000-6737&journal_name=生物物理学报&referenced_num=0&reference_num=6