%0 Journal Article
%T Setup of an In Vitro Test System for Basic Studies on Biofilm Behavior of Mixed-Species Cultures with Dental and Periodontal Pathogens
%A Kerstin Standar
%A Bernd Kreikemeyer
%A Sylvio Redanz
%A Wanja L. M¨šnter
%A Michael Laue
%A Andreas Podbielski
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0013135
%X Caries and periodontitis are important human diseases associated with formation of multi-species biofilms. The involved bacteria are intensively studied to understand the molecular basis of the interactions in such biofilms. This study established a basic in vitro single and mixed-species culture model for oral bacteria combining three complimentary methods. The setup allows a rapid screening for effects in the mutual species interaction. Furthermore, it is easy to handle, inexpensive, and reproducible.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013135