%0 Journal Article
%T Sedative and Anticonvulsant Properties of the Decoction 
of Balanites aegyptiaca (Balanitaceae)
%A Elisabeth Ngo Bum
%A Neteydji Sidiki
%A Taiwe
%A Paul Fasutin Seke Etet
%A Frededic Maidawa
%A Silvere Vincent Rakotonirina
%A Alice Rakotonirina
%J Journal of Animal and Veterinary Advances
%D 2012
%I Medwell Online
%X The decoction of Balanites aegyptiaca, a plant used in traditional medicine in Africa for many diseases, possesses anticonvulsant and sedative activity in mice. This decoction protected mice against strychnine- and pentylenetetrazol-induced seizures. But Balanites aegyptiaca decoction had no effect against picrotoxin-induced seizures. In the other side, the decoction of Balanites aegyptiaca potentiated sleep-induced by diazepam. The total sleep time of the control group was multiply by 4 in the presence of the decoction at a dose of 1000 mg /kg (from 12 to 59 min). With these effects, the decoction of Balanites aegyptiaca L. seem to posses sedative and anticonvulsant properties that might explain its use as a traditional medicine for epilepsy in Africa.
%U http://www.medwellonline.net/abstract/?doi=javaa.2005.34.38