%0 Journal Article
%T Effect of a Polyherbal Formulation (Diarun plus) on Streptozotocin Induced Experimental Diabetes
%A G. Senthilvel
%A M. Jegadeesan
%A Anoop Austin
%A P. Thirugnanasambantham
%A E. Mayisvren
%A M. Balasubramanian
%A N. Narayanan
%A S. Viswanathan
%J International Journal of Tropical Medicine
%D 2012
%I 
%X Diarun plus was evaluated for its therapeutic antihyperglycemic activity in streptozotocin-induced diabetes in animal models. It was effective in controlling hyperglycemic status in rats and mice. The drug (500 mg/kg) showed significant antidiabetic property as judged by serum glucose levels. However, it did not significantly influence the levels of serum insulin in both diabetic and normoglycemic rats. This is a promising drug to develop standardized phytomedicine for diabetes mellitus. The findings suggest that it can be considered as a therapeutic agent, wherever elevated glycemic status is observed.
%U http://www.medwellonline.net/abstract/?doi=ijtmed.2006.88.92