%0 Journal Article
%T Suppressive Effects of Vascular Endothelial Growth Factor-B on Tumor Growth in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis
%A Imke Albrecht
%A Lucie Kopfstein
%A Karin Strittmatter
%A Tibor Schomber
%A Annelie Falkevall
%A Carolina E. Hagberg
%A Pascal Lorentz
%A Michael Jeltsch
%A Kari Alitalo
%A Ulf Eriksson
%A Gerhard Christofori
%A Kristian Pietras
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0014109
%X The family of vascular endothelial growth factors (VEGF) contains key regulators of blood and lymph vessel development, including VEGF-A, -B, -C, -D, and placental growth factor. The role of VEGF-B during physiological or pathological angiogenesis has not yet been conclusively delineated. Herein, we investigate the function of VEGF-B by the generation of mouse models of cancer with transgenic expression of VEGF-B or homozygous deletion of Vegfb.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0014109