%0 Journal Article
%T POLD2 and KSP37 (FGFBP2) Correlate Strongly with Histology, Stage and Outcome in Ovarian Carcinomas
%A Bente Vilming Elgaaen
%A Kari Bente Foss Haug
%A Junbai Wang
%A Ole Kristoffer Olstad
%A Dario Fortunati
%A Mathias Onsrud
%A Anne Cathrine Staff
%A Torill Sauer
%A Kaare M. Gautvik
%J PLOS ONE
%D 2012
%I Public Library of Science (PLoS)
%R 10.1371/journal.pone.0013837
%X Epithelial ovarian cancer (EOC) constitutes more than 90% of ovarian cancers and is associated with high mortality. EOC comprises a heterogeneous group of tumours, and the causes and molecular pathology are essentially unknown. Improved insight into the molecular characteristics of the different subgroups of EOC is urgently needed, and should eventually lead to earlier diagnosis as well as more individualized and effective treatments. Previously, we reported a limited number of mRNAs strongly upregulated in human osteosarcomas and other malignancies, and six were selected to be tested for a possible association with three subgroups of ovarian carcinomas and clinical parameters.
%U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0013837