%0 Journal Article %T Large-Scale Candidate Gene Analysis of HDL Particle Features %A Bernhard M. Kaess %A Maciej Tomaszewski %A Peter S. Braund %A Klaus Stark %A Suzanne Rafelt %A Marcus Fischer %A Robert Hardwick %A Christopher P. Nelson %A Radoslaw Debiec %A Fritz Huber %A Werner Kremer %A Hans Robert Kalbitzer %A Lynda M. Rose %A Daniel I. Chasman %A Jemma Hopewell %A Robert Clarke %A Paul R. Burton %A Martin D. Tobin %A Christian Hengstenberg %A Nilesh J. Samani %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0014529 %X HDL cholesterol (HDL-C) is an established marker of cardiovascular risk with significant genetic determination. However, HDL particles are not homogenous, and refined HDL phenotyping may improve insight into regulation of HDL metabolism. We therefore assessed HDL particles by NMR spectroscopy and conducted a large-scale candidate gene association analysis. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0014529