%0 Journal Article
%T The Reno-Protective Effects of Coconut Water on the Kidneys of Diabetic Wistar Rats
%J Journal of Health Science
%@ 2166-5990
%D 2012
%I 
%R 10.5923/j.health.20120201.01
%X Diabetes Mellitus is one of the leading causes of end stage renal failure. In this present study the remedial effect of coconut water on alloxan-induced diabetes mellitus on the total body weight, kidney function and kidney cyto-architecture were studied. A total of eighteen (18) wistar rats were randomly divided into three experimental groups (n=6). Group I (Control) was fed on rat chow and water ad libitum and Group II and III were made diabetic by single intra peritoneal dose of 150mg/kg body weight of alloxan monohydrate. Group II were fed rat chow and water ad libitum and Group III fed a rat chow and coconut water ad libitum for 30 days. The result showed a statistical significant (P   0.05) reduction in weight, a significant increase in the renal function parameters (urea, creatinine, potassium, sodium and bicarbonate) due to diabetes and a significant reduction in these parameters following the administration of coconut water. The renal cyto-architecture also showed a protective/regenerative effect following treatment with coconut water. This finding may be beneficial in preventing kidney damage in diabetic patients.
%K Renal Histology
%K Renal Function Test
%K Coconut (Cocos Nucifera) Water
%U http://article.sapub.org/10.5923.j.health.20120201.01.html