%0 Journal Article
%T The Development of Fluorescence Imaging Systems for Clinical Applications - Part I, Broad-Field Fluorescence Imaging
%J International Journal of Instrumentation Science
%@ 2324-9986
%D 2012
%I 
%R 10.5923/j.instrument.20120102.02
%X This article proposed a novel classification on fluorescence imaging for clinical applications, and presented a camera-based instrument to verify the functions by an animal mode. The imaging technologies of fluorescence currently are developed in biological medicine included broad-field fluorescence imaging, point-probe fluorescence imaging, and cross-sectional endoluminal fluorescence imaging respectively. This periodicalĄ¯s editor introduced broad-field fluorescence imagingĄ¯s latest developments in technology in this issue, and illustrated a photo retouching system for decreasing the fluorescence signal-to-noise ratio in photodynamic therapy (PDT) for skin cancer. The animal test also verified that this camera-based instrument still could capture the red fluorescence under a low-dosed light sensitive drug and the scope of distribution of melanoma cells in the vein could clearly be observed.
%K Broad-Field Fluorescence Imaging
%K Photo Retouching
%K Signal-To-Noise
%K Photodynamic Therapy (PDT)
%U http://article.sapub.org/10.5923.j.instrument.20120102.02.html