%0 Journal Article
%T In VitroBioactivity of Collagen/Calcium Phosphate Silicate Composites, Cross-Linked with Chondroitin Sulfate
%J International Journal of Materials and Chemistry
%@ 2166-5354
%D 2012
%I 
%R 10.5923/j.ijmc.20120201.01
%X In this work we present the experimental results on synthesis structure and in vitro bioactivity of collagen (C)/calcium phosphate silicate (CPS)/chondroitin sulfate (ChS) composites with C/CPS ratio of 25:75 wt. % and 75:25wt. %. The synthesized composites were characterized by XRD, FTIR and SEM/EDS. XRD and FTIR before in vitro test proved that the carbonate containing hydroxyapatite (CO3HA) formed in situ. After in vitro test for 3 days in 1.5 SBF, the nucleation of B-type CO3HA was estimated on the obtained C/CPS=75:25 wt. % composite with cauliflower-like assembly. On the C/CPS=25:75 wt. % amorphous hydroxyapatite (HA) layer was observed.
%K Collagen
%K Calcium Phosphate Silicate
%K in Vitro Bioactivity
%K Chs
%U http://article.sapub.org/10.5923.j.ijmc.20120201.01.html