%0 Journal Article
%T 3-(4-Bromobenzoyl)prop-2-enoic acid as Precursor in Synthesis of Some Important Heterocyclic Compounds
%J American Journal of Chemistry
%@ 2165-8781
%D 2012
%I 
%R 10.5923/j.chemistry.20120201.01
%X The present work deals with the generation and synthesis of different heterocycles such as 2-pyrimidine thione, pyrane, pyridine and phthalazinone derivative via the treatment of 3-(4-bromobenzoyl)prop-2-enoic acid with thiourea, ethylcyanoacetate malononitrile& acetylacetone in presence of amm.acetate and/or piperidine respectively.Additionally, utility of 2-amino-3-cyano-4-carboxy-6-(4-bromophenyl)3,4-dihydropyridine (4) as a key starting material to synthesize some important heterocycles include fused pyrido-pyrimidine,fused pyrido- pyridazinopyrimidine and interesting diheterocyclic amines.
%K 3-Aroyl prop-2-enoic acid
%K pyrrole
%K furan
%K Pyridone
%K Ethylnicotinate
%K pyrane
%K phthalazinone
%K 2-pyrimidine thione
%K pyridopyrimidine
%K pyridazino-pyrimidine
%U http://article.sapub.org/10.5923.j.chemistry.20120201.01.html