%0 Journal Article
%T Emerging treatment approaches in acute lymphoblastic and acute myeloid leukemias
%A Thomas X
%J Blood and Lymphatic Cancer: Targets and Therapy
%D 2012
%I 
%R http://dx.doi.org/10.2147/BLCTT.S15567
%X ging treatment approaches in acute lymphoblastic and acute myeloid leukemias Review (1767) Total Article Views Authors: Thomas X Published Date March 2012 Volume 2012:2 Pages 57 - 76 DOI: http://dx.doi.org/10.2147/BLCTT.S15567 Received: 16 November 2011 Accepted: 17 January 2012 Published: 08 March 2012 Xavier Thomas Hospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Service d'H¨Śmatologie Clinique, Pavillon Marcel B¨Śrard, Bat.1G, Pierre B¨Śnite, France Abstract: The choice of treatment approach in acute leukemia depends on well-established prognostic factors. A number of features can predict the outcome of treatment including cytogenetics and an increasing list of molecular features. These are increasingly being used to direct postinduction therapy and support risk-adapted treatments that should achieve optimal results while minimizing nonrelapse mortality. In addition, they are also molecular targets for a new generation of small molecule inhibitors that are in early development and promise to further improve outcomes in the coming decade.
%K acute myeloid leukemia
%K acute lymphoblastic leukemia
%K treatment
%K targeted therapy
%U https://www.dovepress.com/emerging-treatment-approaches-in-acute-lymphoblastic-and-acute-myeloid-peer-reviewed-article-BLCTT