%0 Journal Article
%T Neuropsychiatric effects of tenofovir in comparison with other antiretroviral drugs
%A Ferrer K
%A Rakhmanina N
%J Neurobehavioral HIV Medicine
%D 2013
%I 
%R http://dx.doi.org/10.2147/NBHIV.S24888
%X ropsychiatric effects of tenofovir in comparison with other antiretroviral drugs Review (472) Total Article Views Authors: Ferrer K, Rakhmanina N Published Date January 2013 Volume 2013:5 Pages 1 - 10 DOI: http://dx.doi.org/10.2147/NBHIV.S24888 Received: 18 October 2012 Accepted: 20 December 2012 Published: 23 January 2013 Kathleen Ferrer,1,2 Natella Rakhmanina1,2 1Department of Pediatrics, George Washington University School of Medicine, Washington, DC, USA; 2Health Sciences Children's National Medical Center, Washington, DC, USA Abstract: Tenofovir is a widely used antiretroviral medication indicated to treat adults and children infected with HIV. Current guidelines for the management of HIV infection recommend tenofovir disoproxil fumarate (TDF) as a component of the preferred first-line combination antiretroviral therapy. The efficacy, tolerability, prolonged half-life allowing for once-daily administration, and availability as a component of several fixed-dose formulations make TDF an attractive choice for treatment-naive and treatment-experienced HIV-infected patients. TDF is also widely used as a component of postexposure prophylaxis in noninfected individuals. Most importantly, it has been recently approved for use as pre-exposure prophylaxis for noninfected adults and adolescents to reduce the risk of HIV transmission. With increasing use of TDF among adults and children, understanding of the potential for drug-associated side effects is important. This review focuses on the neuropsychiatric effects of tenofovir in adults and children with HIV infection in comparison with other antiretroviral drugs.
%K HIV
%K tenofovir
%K neuropsychiatric effects
%U https://www.dovepress.com/neuropsychiatric-effects-of-tenofovir-in-comparison-with-other-antiret-peer-reviewed-article-NBHIV