%0 Journal Article
%T Phosphorylation at endothelial cell¨Ccell junctions: Implications for VE-cadherin function
%A Ilse Timmerman
%A Peter L Hordijk
%A Jaap D van Buul
%J Cell Health and Cytoskeleton
%D 2010
%I 
%R http://dx.doi.org/10.2147/CHC.S9590
%X sphorylation at endothelial cell¨Ccell junctions: Implications for VE-cadherin function Review (4016) Total Article Views Authors: Ilse Timmerman, Peter L Hordijk, Jaap D van Buul Published Date May 2010 Volume 2010:2 Pages 23 - 31 DOI: http://dx.doi.org/10.2147/CHC.S9590 Ilse Timmerman, Peter L Hordijk, Jaap D van Buul Department of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, The Netherlands Abstract: Endothelial cell¨Ccell junctions are strictly regulated in order to control the barrier function of endothelium. Vascular endothelial (VE)-cadherin is one of the proteins that is crucial in this process. It has been reported that phosphorylation events control the function of VE-cadherin. This review summarizes the role of VE-cadherin phosphorylation in the regulation of endothelial cell¨Ccell junctions and highlights how this affects vascular permeability and leukocyte extravasation.
%K endothelium
%K VE-cadherin
%K junctions
%K barrier
%K phosphorylation
%U https://www.dovepress.com/phosphorylation-at-endothelial-cellndashcell-junctions-implications-fo-peer-reviewed-article-CHC