%0 Journal Article
%T A review of the potential therapeutic role of statins in the treatment of Alzheimer＊s disease: current research and opinion
%A S芍nchez-Ferro A
%A Benito-Le車n J
%A Mitchell AJ
%A Bermejo-Pareja F
%J Neuropsychiatric Disease and Treatment
%D 2013
%I Dove Medical Press
%R http://dx.doi.org/10.2147/NDT.S29105
%X review of the potential therapeutic role of statins in the treatment of Alzheimer＊s disease: current research and opinion Review (1364) Total Article Views Authors: S芍nchez-Ferro A, Benito-Le車n J, Mitchell AJ, Bermejo-Pareja F Published Date January 2013 Volume 2013:9 Pages 55 - 63 DOI: http://dx.doi.org/10.2147/NDT.S29105 Received: 08 October 2012 Accepted: 08 November 2012 Published: 04 January 2013 芍lvaro S芍nchez-Ferro,1每4 Juli芍n Benito-Le車n,1每3 Alex J Mitchell,5 F谷lix Bermejo-Pareja1每3 1Department of Neurology, University Hospital 12 de Octubre, Madrid, Spain; 2Department of Medicine, Complutense University, Madrid, Spain; 3Centro de Investigaci車n Biom谷dica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain; 4Instituto de Salud Carlos III, Madrid, Spain; 5Department of Psycho-oncology, Leicestershire Partnership NHS Trust and University of Leicester, Leicester, UK Abstract: Alzheimer＊s disease is one of the most prevalent neurodegenerative disorders. However, there is no current treatment, which definitively influences disease progression over a sustained period. Numerous studies linking an increase in serum cholesterol, mainly during midlife, with the pathogenic process of Alzheimer＊s disease have been published. Therefore, the role of statins as a therapy in this disorder may be of great interest. The aim of the present review is to summarize of the role of statins in the treatment of Alzheimer＊s disease.
%K animal models
%K epidemiology
%K HMGCoA-inhibitors
%K clinical trials
%K prevention
%K cognitive function
%U https://www.dovepress.com/a-review-of-the-potential-therapeutic-role-of-statins-in-the-treatment-peer-reviewed-article-NDT