%0 Journal Article %T A modified deep sclerectomy with or without external trabeculectomy: a comparative study %A George Kitsos %A Miltiades Aspiotis %A Yannis Alamanos %A et al %J Clinical Ophthalmology %D 2010 %I %R http://dx.doi.org/10.2147/OPTH.S10350 %X modified deep sclerectomy with or without external trabeculectomy: a comparative study Original Research (3047) Total Article Views Authors: George Kitsos, Miltiades Aspiotis, Yannis Alamanos, et al Published Date June 2010 Volume 2010:4 Pages 557 - 564 DOI: http://dx.doi.org/10.2147/OPTH.S10350 George Kitsos1, Miltiades Aspiotis1, Yannis Alamanos2, Konstantinos Psilas1 1Department of Ophthalmology, Medical School, University of Ioannina, Ioannina, Greece; 2Department of Hygiene and Epidemiology, Medical School, University of Patras, Patras, Greece Purpose: To determine whether the removal of the inner wall of Schlemm¡¯s canal (external trabeculectomy) improves the effectiveness of a modified method of deep sclerectomy (DS), which we will call ¡°reversed¡± deep sclerectomy (RDS). Materials and method: We conducted a prospective study of two groups of patients. Group A included 22 eyes of 18 patients with open angle glaucoma (OAG) under maximum medical treatment, which underwent RDS ¨C a modified method of performing DS ¨C with the removal of the inner wall of Schlemm¡¯s canal (external trabeculectomy) and without using any implant. Group B included 20 eyes of 17 patients which had undergone RDS alone. Demographic and tonometric data of patients of Group A revealed no significant difference from data of patients in Group B. A mean follow up period for Group A was 22.8 months and for Group B was 23.4 months. The outcome of the operations was termed a total success when intraocular pressure (IOP) was <21 mmHg postoperatively, without additional treatment, relative success when IOP was <21 mmHg with additional treatment and a total failure when IOP > 21 mmHg with medical treatment. Results: Total success was achieved in 18/22 eyes (81.8%) for Group A and in 8/20 eyes (40%) for Group B (P < 0.05). Relative success was achieved in 22/22 (100%) for Group A and in 17/20 eyes (85%) in Group B (P = NS). Total failure occurred in 0/22 eyes (0%) in Group A and in 3/20 (15%) eyes in Group B (P = NS). The mean postoperative IOP in Group A was 13.5 ¡À 2.8 mmHg with a reduction of 12.4 ¡À 4.6 mmHg (48.1%) and in Group B mean postoperative IOP was 18 ¡À 4.3 mmHg with a reduction of 6.2 ¡À 6.9 (25.6%) (P < 0.001). Mean drug reduction postoperatively was 3.2 ¡À 0.9 drugs in Group A and 1.7 ¡À 1.2 in Group B (P < 0.001). Conclusion: In the follow up time during which the two groups were under study (12¨C36 months), the removal of the inner wall of Schlemm¡¯s canal while performing RDS proves an important factor in improving its effectiveness. %K modified deep sclerectomy %K external trabeculectomy %U https://www.dovepress.com/a-modified-deep-sclerectomy-with-or-without-external-trabeculectomy-a--peer-reviewed-article-OPTH