%0 Journal Article
%T Pelvic exenteration for colorectal cancer: oncologic outcome in 59 patients at a single institution
%A L¨®pez-Basave HN
%A Morales-V¨¢squez F
%A Herrera-G¨®mez ¨¢
%A Padilla Rosciano A
%A Meneses-Garc¨ª¨¢ A
%A Ruiz-Molina JM
%J Cancer Management and Research
%D 2012
%I 
%R http://dx.doi.org/10.2147/CMAR.S34545
%X exenteration for colorectal cancer: oncologic outcome in 59 patients at a single institution Original Research (1117) Total Article Views Authors: L¨®pez-Basave HN, Morales-V¨¢squez F, Herrera-G¨®mez ¨¢, Padilla Rosciano A, Meneses-Garc¨ª¨¢ A, Ruiz-Molina JM Published Date October 2012 Volume 2012:4 Pages 351 - 356 DOI: http://dx.doi.org/10.2147/CMAR.S34545 Received: 01 June 2012 Accepted: 14 August 2012 Published: 11 October 2012 Horacio N L¨®pez-Basave, Flavia Morales-V¨¢squez, ¨¢ngel Herrera-G¨®mez, Alejandro Padilla Rosciano, Abelardo Meneses-Garc¨ªa, Juan M Ruiz-Molina Department of Gastroenterology, Instituto Nacional de Cancerolog¨ªa (INCan), Mexico City, Mexico Background: Pelvic exenteration (PE) continues to be the only curative option in selected patients with advanced or recurrent pelvic neoplasms. A current debate exists concerning the appropriate selection of patients for PE, with the most important factor being the absence of extrapelvic disease. Aim: To evaluate the outcome of patients submitted to exenterative surgery. Patients and methods: A review of the clinical charts of patients with colorectal cancer who underwent PE between January 1994 and June 2010 at the Institute National of Cancerolog¨ªa in Mexico City was performed. Results: We selected 59 patients, 53 of whom were females (90%), and six of whom were males (10%). Mean age at the time of diagnosis was 50 years (range, 21-77 years). A total of 51 patients underwent posterior PE (86%), and eight patients underwent total PE (14%). Operative mortality occurred in two cases (3%), and 29 patients developed complications (49%). Overall, 11 patients (19%) experienced local failure with mean disease-free survival time of 10.2 months. After a mean follow-up of 28.3 months, nine patients are still alive without evidence of the disease (15%). Conclusions: PE should be considered in advanced colorectal cancer without extrapelvic metastatic disease. PE is accompanied by considerable morbidity (49%) and mortality (3%), but local control is desirable. Overall survival justifies the use of this procedure in patients with primary or recurrent locally advanced rectal cancer.
%K pelvic exenteration
%K colorectal cancer
%U https://www.dovepress.com/pelvic-exenteration-for-colorectal-cancer-oncologic-outcome-in-59-pati-peer-reviewed-article-CMAR