%0 Journal Article
%T Goals for rheumatoid arthritis: treating to target or treating to prevent?
%A Yang M
%A Guo MY
%J Open Access Rheumatology: Research and Reviews
%D 2012
%I Dove Medical Press
%R http://dx.doi.org/10.2147/OARRR.S32493
%X als for rheumatoid arthritis: treating to target or treating to prevent? Review (2266) Total Article Views Authors: Yang M, Guo MY Published Date July 2012 Volume 2012:4 Pages 81 - 86 DOI: http://dx.doi.org/10.2147/OARRR.S32493 Received: 01 April 2012 Accepted: 07 May 2012 Published: 10 July 2012 Min Yang, Mingyang Guo Rheumatology Center, PLA General Hospital of Chengdu Military Area Command, Chengdu, Sichuan Province, PR China Although treat-to-target goals for rheumatoid arthritis (RA) have been well-established through several guidelines in recent years, concerns regarding treat-to-prevent goals for RA remain unclear. RA patients are typically subjected to over- or under-treatment because it is difficult for clinicians to determine the prognosis of RA patients. This typically results in failure to select and identify patient subsets that should receive monotherapy or combination therapy to treat early RA. Understanding treat-to-prevent goals, as well as unfavorable prognoses, risk factors, and prediction methods for RA, is therefore critical for making treatment decisions. Rapid radiographic progression plays a central role in contributing to other composite RA indices, so this may be the best method for defining treat-to-prevent goals for RA. Accordingly, risk factors of rapid radiographic progression have been defined and two prediction models were retrospectively derived based on clinical trial data. Additional studies are required to develop risk models that can be used for accurate predictions.
%K rapid radiographic progression
%K prognosis
%K risk factors
%K prediction models
%U https://www.dovepress.com/goals-for-rheumatoid-arthritis-treating-to-target-or-treating-to-preve-peer-reviewed-article-OARRR