%0 Journal Article %T Endothelial Dysfunction, Erectile Dysfunction and Phosphodiesterase 5 Inhibitors. An Update of the Current Data and Future Perspectives %A Angelis Konstantinopoulos %A Konstantinos Giannitsas %A Spiros Raptis and Petros Perimenis %J Drug Target Insights %D 2012 %I %X Endothelial dysfunction is a pathological entity that multiply affects the health status. Erectile dysfunction is being recognized as a condition that is strongly interrelated with endothelial dysfunction, being a vascular event itself. Oral pharmacotherapy for erectile dysfunction has provided us with a new armamentarium on this condition. Phosphodiesterase 5 inhibitors have been investigated and proved useful in clinical practice for erectile dysfunction but in addition to this, the results seem promising of a benefi cial effect on endothelial dysfunction, as well. %U http://www.la-press.com/endothelial-dysfunction-erectile-dysfunction-and-phosphodiesterase-5-i-article-a258