%0 Journal Article
%T A comparison of cytokine responses during prolonged cycling in normal and hot environmental conditions
%A Ludmila M Cosio-Lima
%A Bhargav V Desai
%A Petra B Schuler
%A et al
%J Open Access Journal of Sports Medicine
%D 2011
%I Dove Medical Press
%R http://dx.doi.org/10.2147/OAJSM.S15980
%X comparison of cytokine responses during prolonged cycling in normal and hot environmental conditions Original Research (3918) Total Article Views Authors: Ludmila M Cosio-Lima, Bhargav V Desai, Petra B Schuler, et al Published Date January 2011 Volume 2011:2 Pages 7 - 11 DOI: http://dx.doi.org/10.2147/OAJSM.S15980 Ludmila M Cosio-Lima, Bhargav V Desai, Petra B Schuler, Lesley Keck, Logan Scheeler Department of Health, Leisure, and Exercise Science, University of West Florida, Pensacola, FL, USA Purpose: Components of immune function are affected by physical activity in an adverse environment. The purpose of this study was to compare plasma differences in inflammatory cytokines including tumor necrosis factor ¦Á (TNF-¦Á) and interleukin 6 (IL-6), in addition to the stress hormone cortisol, during prolonged cycling under normal and hot environmental conditions in elite cyclists. Methods and design: Six trained elite male cyclists (27 ¡À 8 years; 75.5 ¡À 4 kg; maximum oxygen uptake [VO2max] = 66 ¡À 6 mL/kg/min, mean ¡À SD). The cyclists biked for 2.5 h at their prescribed 60% maximum exercise workload (Wmax) or 75% VO2max either in an environmental chamber set at 15¡ãC and 40% relative humidity (NEUTRAL) or at 35¡ãC and 40% relative humidity (HOT). The cyclists were given 4 mL of water/kg body weight every 15 min under both conditions. Results: Total cortisol concentrations were elevated (P < 0.05) immediately postexercise and 12 h postexercise in both the NEUTRAL and HOT conditions. TNF-¦Á concentrations were only significantly (P = 0.045) elevated postexercise in HOT conditions. During the HOT conditions, a significant (P = 0.006 and 0.007, respectively) difference in IL-6 was seen immediately after and 12 h postexercise. During the NEUTRAL condition, IL-6 was only significantly elevated postexercise (P < 0.05). Conclusions: Heat exposure during a long bout of exercise is sufficient to elicit stress response in elite cyclists. However, the degree of release of anti-inflammatory and proinflammatory cytokines might be related to several factors that include the athlete¡¯s fitness level, hydration status, exercise intensity, and length of exposure to hot environments.
%K cytokines
%K inflammation
%K heat
%K exercise
%K performance
%U https://www.dovepress.com/a-comparison-of-cytokine-responses-during-prolonged-cycling-in-normal--peer-reviewed-article-OAJSM