%0 Journal Article
%T Running a marathon from -45ˇăC to +55ˇăC in a climate chamber: a case study
%A K lin K
%A Knechtle B
%A R¨ąst CA
%A Mydlak K
%A Rosemann T
%J Open Access Journal of Sports Medicine
%D 2012
%I Dove Medical Press
%R http://dx.doi.org/10.2147/OAJSM.S36808
%X nning a marathon from -45ˇăC to +55ˇăC in a climate chamber: a case study Case report (1119) Total Article Views Authors: K lin K, Knechtle B, R¨ąst CA, Mydlak K, Rosemann T Published Date October 2012 Volume 2012:3 Pages 131 - 145 DOI: http://dx.doi.org/10.2147/OAJSM.S36808 Received: 07 August 2012 Accepted: 03 September 2012 Published: 25 October 2012 Kaspar K lin,1 Beat Knechtle,1,2 Christoph Alexander R¨ąst,1 Karsten Mydlak,3 Thomas Rosemann1 1Institute of General Practice and Health Services Research, University of Zurich, Zurich; 2Gesundheitszentrum St Gallen, St Gallen, Switzerland; 3Gemeinschaftslabor Cottbus, Medizinisches Versorgungszentrum f¨ąr Labormedizin, Mikrobiologie und Infektionsepidemiologie, Cottbus, Germany Background: We describe a runner who completed a self-paced marathon (42.195 km) in a climate chamber with a temperature difference of 100ˇăC, starting at an ambient temperature (Tambient) of  45ˇăC and finishing at an Tambient of +55ˇăC. Methods: Tambient was set at  45ˇăC at the start, and was steadily increased at a rate of 1ˇăC at 4.5-minute intervals to +55ˇăC. Before the start, after every 10.5 km, and at the end of the marathon, body mass, urine, and sweat production were measured and samples of venous blood and urine were collected. The runnerˇŻs temperature was recorded every 10 seconds at four sites, ie, the rectum for body core temperature (Tcore), and at the forehead, right wrist, and right ankle for surface temperatures (Tskin). Results: The subject took 6.5 hours to complete the marathon, during which Tcore varied by 0.9ˇăC (start 37.5ˇăC, peak 38.4ˇăC). The largest difference (¦¤) of Tskin was recorded at the ankle (¦¤16ˇăC). The calculated amount of sweat produced increased by 888% from baseline. In the blood samples, myoglobin (+250%) showed the highest change. Of the pituitary hormones, somatotropic hormone (+391%) and prolactin (+221%) increased the most. Regarding fluid regulation hormones, renin (+1145%) and aldosterone (+313%) showed the greatest increase. Conclusion: These results show that running a marathon in a climate chamber with a total ¦¤Tambient of 100ˇăC is possible, and that the Tambient to Tcore relationship is maintained. These results may offer insight into regulatory mechanisms to avoid hypothermia and hyperthermia. The same study is to be performed using more subjects with the same characteristics to validate the present findings.
%K endocrine regulation
%K thermoregulation
%K skin temperature
%K ambient temperature
%K sweat production
%U https://www.dovepress.com/running-a-marathon-from--45degc-to-55degc-in-a-climate-chamber-a-case--peer-reviewed-article-OAJSM