%0 Journal Article
%T C1 Esterase Inhibitor (Human) for the Treatment of Acute Hereditary Angioedema
%A Solange Oliveira Rodrigues Valle
%A Alfeu Tavares Fran a
%A Regis A. Campos and Anete Sevciovic Grumach
%J Clinical Medicine Insights: Blood Disorders
%D 2012
%I 
%R 10.4137/CMBD.S4090
%X Hereditary angioedema (HAE) is a relatively rare disease characterized by acute episodes of swelling. These swellings can be disfiguring, painful and life-threatening. Since the symptoms occur in different areas and most patients experience a delay in their diagnosis, resulting in unnecessary suffering and dangerous situations. HAE can have a tremendous impact on the quality of life. The major genetic deficiency in this disorder is either an absent or nonfunctional C1INH which regulates the complement, fibrinolitic, kalikrein and plasmin pathways.
%U http://www.la-press.com/c1-esterase-inhibitor-human-for-the-treatment-of-acute-hereditary-angi-article-a2854