%0 Journal Article
%T Commonality Between Diabetes and Alzheimer¡¯s Disease and A New Strategy for the Therapy
%A Lin Li
%J Clinical Medicine Insights: Pathology
%D 2012
%I 
%X A surprising common pathological processes is found between Alzheimer¡¯s disease (AD) and type 2 diabetes mellitus (T2DM)[1]. AD and T2DM share some common pathological processes: Amyloid ¦Â (A¦Â), ¦Ó hyperphosphoralation, insulin abnormality. Disturbance in insulin signalling is not only involved in blood glucose level but also in numerous degenerative processes. Glucagon-like peptide 1 (GLP-1) has attracted substantial attention for its advantage in treating T2DM. GLP-1 can reduce A¦Â levels in brain. All these encourage us in a medical hypothesis: that is, that GLP-1 is a promising agent in the therapy of AD.
%U http://www.la-press.com/commonality-between-diabetes-and-alzheimers-disease-and-a-new-strategy-article-a928