%0 Journal Article %T A Blend of Phellodendron and Crape Myrtle Improves Glucose Tolerance in Exercise-Trained Men %A Robert E. Canale %A Tyler M. Farney %A Cameron G. McCarthy and Richard J. Bloomer %J Nutrition and Metabolic Insights %D 2012 %I %R 10.4137/NMI.S7837 %X Background: The purpose of this study was to investigate the acute effects of a nutritional supplement containing a proprietary blend of Phellodendron and Crape Myrtle on serum glucose and insulin in response to a modified oral glucose tolerance test (OGTT). Methods: Using a randomized, double-blind, cross-over design, 10 exercise-trained, non-diabetic men reported to the lab in a 10 hour fasted state, on two different mornings separated by 1¨C2 weeks, and were subjected to an OGTT by ingesting a 75 gram dextrose solution. Fifteen minutes prior to the OGTT subjects ingested either a dietary supplement containing a blend of Phellodendron and Crape Myrtle (SUPP) or a placebo (PLA). Blood samples were collected before ingestion of the SUPP or PLA and at 15, 30, 45, 60, and 75 minutes post-ingestion of the dextrose load. Samples were analyzed for serum glucose and insulin. Results: In relation to serum glucose, a condition effect was noted (P = 0.01), with values lower for SUPP compared to PLA. In relation to serum insulin, a trend for a condition effect was noted (P = 0.06), with values lower for SUPP compared to PLA. Conclusion: These findings indicate that acute ingestion of a dietary supplement containing a blend of Phellodendron and Crape Myrtle can lower the serum glucose response to a modified OGTT, while resulting in a non-significant attenuation in insulin response. These data are specific to a small sample of exercise-trained, non-diabetic men. %U http://www.la-press.com/a-blend-of-phellodendron-and-crape-myrtle-improves-glucose-tolerance-i-article-a2827