%0 Journal Article
%T The Characterization of Cell Line CRL-2335 as a Basal-Like Breast Carcinoma Model
%A Lori A. Hill Neves
%A Lishann Ingram and Melissa B. Davis
%J Breast Cancer: Basic and Clinical Research
%D 2012
%I 
%R 10.4137/BCBCR.S7087
%X Basal-like breast cancer has been reported to be the most aggressive and deadly carcinoma sub-type. Patients diagnosed with this subtype have a less than 50% five-year survival. In addition, many studies have reported that this sub-type is more prevalent in specific ethnic groups and is believed to be a key factor that drives certain ethnic disparities in mortality. In order to effectively study this sub-type and determine unique gene expression and biochemical pathways which sustain this cancer's growth, we sought to identify human breast cancer cell lines that represent a model for the basal-like subtype. Here, we report our findings which indicate the African American cell line CRL-2335 is a true representative of basal-like breast carcinoma.
%U http://www.la-press.com/the-characterization-of-cell-line-crl-2335-as-a-basal-like-breast-carc-article-a2610