%0 Journal Article
%T A review of the incidence and survival of childhood and adolescent cancer and the effects of treatment on future fertility and endocrine development
%A MH Botha
%A TF Kruger
%J South African Journal of Obstetrics and Gynaecology
%D 2012
%I 
%X Cancer is not uncommon in children. The reproductive system is an important site for late effects of cancer treatment, and normal pubertal development depends on an undamaged hypothalamic-pituitary-gonadal axis. Fertility compromise can occur due to chemotherapy, radiotherapy to the hypothalamic-pituitary-gonadal axis, or surgery. Cryopreservation techniques of germ cells are improving and may offer hope for fertility preservation.
%U http://www.ajol.info/index.php/sajog/article/view/76918