%0 Journal Article
%T Association of the polymorphism in the 5กฏ flanking region of the ovine IGF-I gene with growth traits in the Baluchi sheep
%A M Tahmoorespur
%A MV Valeh
%A MR Nassiry
%A AH Moussavi
%A M Ansary
%J South African Journal of Animal Science
%D 2010
%I South African Society for Animal Science
%X The insulin-like growth factor 1 (IGF-I) gene has been described in several studies as a candidate gene for growth traits in farm animals. The present preliminary study attempts to establish associations between growth traits and genetic polymorphisms at the 5กฏ flanking region s IGF-I in the Baluchi sheep. The DNA of 102 sheep of the indigenous Iranian Baluchi breed was evaluated. Polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) analysis of the 5กฏ flanking region (Exon1) of the ovine IGF-I gene revealed three banding patterns (genotypes) named as A/A, A/B and B/B. The evaluation of an association effect between these SSCP patterns with birth weight (BW), weaning weight (WW), and average daily gain from birth to weaning (GBW), weaning to six month (GWS) and from six month to yearling age (GSY) suggest a positive effect of pattern (Genotype) A/B with GBW and weaning weight (WW). Pattern (Genotype) B/B had a superior birth weight when compared to those of individuals with other patterns. Moreover, the A/A pattern (Genotype) appeared favourable for live weight at yearling age. These results confirmed the potential usefulness of this gene in marker-assisted selection programmes for sheep breeding.
%U http://www.ajol.info/index.php/sajas/article/view/65298