%0 Journal Article %T Cowhage-Induced Itch as an Experimental Model for Pruritus. A Comparative Study with Histamine-Induced Itch %A Alexandru D. P. Papoiu %A Hong Liang Tey %A Robert C. Coghill %A Hui Wang %A Gil Yosipovitch %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0017786 %X Histamine is the prototypical pruritogen used in experimental itch induction. However, in most chronic pruritic diseases, itch is not predominantly mediated by histamine. Cowhage-induced itch, on the other hand, seems more characteristic of itch occurring in chronic pruritic diseases. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0017786