%0 Journal Article %T Generic Insect Repellent Detector from the Fruit Fly Drosophila melanogaster %A Zainulabeuddin Syed %A Julien Pelletier %A Eric Flounders %A Rodrigo F. Chitolina %A Walter S. Leal %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0017705 %X Insect repellents are prophylactic tools against a number of vector-borne diseases. There is growing demand for repellents outperforming DEET in cost and safety, but with the current technologies R&D of a new product takes almost 10 years, with a prohibitive cost of $30 million dollar in part due to the demand for large-scale synthesis of thousands of test compounds of which only 1 may reach the market. R&D could be expedited and cost dramatically reduced with a molecular/physiological target to streamline putative repellents for final efficacy and toxicological tests. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0017705