%0 Journal Article %T Functional Expression of the Extracellular Calcium Sensing Receptor (CaSR) in Equine Umbilical Cord Matrix Size-Sieved Stem Cells %A Nicola Antonio Martino %A Anna Lange-Consiglio %A Fausto Cremonesi %A Luisa Valentini %A Michele Caira %A Antonio Ciro Guaricci %A Barbara Ambruosi %A Raffaele Luigi Sciorsci %A Giovanni Michele Lacalandra %A Stephan Joel Reshkin %A Maria Elena Dell'Aquila %J PLOS ONE %D 2012 %I Public Library of Science (PLoS) %R 10.1371/journal.pone.0017714 %X The present study investigates the effects of high external calcium concentration ([Ca2+]o) and the calcimimetic NPS R-467, a known calcium-sensing receptor (CaSR) agonist, on growth/proliferation of two equine size-sieved umbilical cord matrix mesenchymal stem cell (eUCM-MSC) lines. The involvement of CaSR on observed cell response was analyzed at both the mRNA and protein level. %U http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0017714