%0 Journal Article
%T Histological Pattern of Prostatic Diseases in Nigerians
%A AZ Mohammed
%A EJC Nwana
%A AS Anjorin
%J African Journal of Urology
%D 2005
%I 
%X Objective: This is a laboratory-based retrospective study of the histopathological pattern of prostatic lesions seen at Jos University Teaching Hospital (JUTH) over a 10 year period (1989-1998). Material and Methods: In total, 493 prostatic lesions were seen representing 3.2% of the 15,424 surgical specimens obtained during the study period. After histological assessment, the tumors were classified according to the WHO recommendation. Histological grading/scoring of adenocarcinomas was done using the Gleason system. Results: 372 (75.4%) prostatic lesions were benign prostatic hyperplasia (BPH) with co-existing chronic prostatitis in 23.6% of cases. The peak age of occurrence of BPH was in the seventh decade of life. Prostate cancer constituted 121 (24.6%) of all prostatic lesions with a peak age of occurrence in the seventh decade. 94.2% of the cancer cases were adenocarcinomas, while adenosquamous and squamous cell carcinoma represented 1.7% each of cases. Leiomyosarcoma and rhabdomyosarcomawere noted in 0.8% each of cases. The adenocarcinomas were well, moderately and poorly differentiated in 85.1%. 7.9% and 7% of cases, respectively, and incidental carcinoma was detected in 12.3% of cases. The paucity of other rare lesions was also noted and, with few exceptions, the patterns of prostatic lesions were comparable to the findings in other parts of the world. Conclusion: In preparation for a potential future increase in the incidence and mortality rates from prostate cancer, every effort should be made to improve diagnosis, staging and management facilities. Even though a small number of cancer cases was reported in the past, dietary and environmental risk factors may escalate the rates necessitating the need for screening by PSA assays and sextant biopsies under ultrasound guidance. This will ensure early diagnosis and treatment promising an improvement of the survival rates. Mod¨¨le histopathologique des maladies prostatiques chez les Nig¨¦riens Objectifs : C\'est une ¨¦tude r¨¦trospective bas¨¦e sur le r¨¦sultat de laboratoire du mod¨¨le histopathologique des l¨¦sions prostatiques vues ¨¤ l\'h pital universitaire de Jos (JUTH) sur une p¨¦riode de 10 ans (1989-1998). Mat¨¦riel et m¨¦thodes : Un total de 493 l¨¦sions prostatiques ont ¨¦t¨¦ vus repr¨¦sentant 3,2% des 15.424 sp¨¦cimens chirurgicaux re us pendant la p¨¦riode d\'¨¦tude. Apr¨¨s ¨¦valuation histologique, les tumeurs ont ¨¦t¨¦ class¨¦es conform¨¦ment ¨¤ la recommandation d\'OMS. Grade/score histologique des ad¨¦nocarcinomes a ¨¦t¨¦ fait en utilisant le syst¨¨me de Gleason. R¨¦sultats : 372 (75,4%) l¨¦sions prostatiques ¨¦taient ¨¤ type d'hyperplasie prostatique b¨¦nigne (BPH) avec co-existence de la prostatite chronique dans 23,6% des cas. L\'age maximal de l\'occurrence de BPH avait lieu dans la septi¨¨me d¨¦cennie de la vie. Le cancer de prostate a constitu¨¦ 121 (24.6%) de toutes les l¨¦sions prostatiques avec un age maximal d\'occurrence dans la septi¨¨me d¨¦cennie. 94.2% des cas de cancer ¨¦taient des ad¨¦nocarcinomes, alo
%U http://www.ajol.info/index.php/aju/article/view/8082