%0 Journal Article
%T N-6 substituted deoxygenated derivatives of L-like 5'-noraristeromycin
%A Henry Yu
%A Tesfaye Serbessa
%J Bulletin of the Chemical Society of Ethiopia
%D 2010
%I Chemical Society of Ethiopia
%X Several N-6 substituted derivatives (4-11) of (+)-4'-deoxy-5'-noraristeromycin (2) and its unsaturated counterpart (3) have been prepared. The derivatives are designed to systematically vary the hydrophobic/hydrophilic balance of the lead compounds. These compounds were evaluated against a large number of viruses but no significant antiviral activity was observed. Also, no cytotoxicity to host cells was found.   KEY WORDS: L-like, Carbocyclic nucleosides, HBV    Bull. Chem. Soc. Ethiop. 2010, 24(3), 439-446.
%U http://www.ajol.info/index.php/bcse/article/view/60692