%0 Journal Article
%T Isotope-Selective Infrared Spectroscopy Reveals Pathological Changes in the Liver
%A Jana Vranov¨¢
%A Jozef Rosina
%A Ji ¨ª Horak
%A Milu e Hendrichova
%A Karolina Kratka
%J Acta Mechanica Slovaca
%D 2010
%I 
%R 10.2478/v10147-011-0021-0
%X An overview of new diagnostic device IRIS (Wagner Analysen Technik, Germany) is provided. This device uses the 13C stable isotope together with non-dispersive infrared selective spectroscopy for non - invasive quantification of hepatic function parameters, including kinetics (type of liver damage) and capacity (percentage of recovery yield of the liver). The short physical principle of infrared spectroscopy and acousto-optical detector of IRIS was presented. In the final section we verified the diagnostic quality of this new diagnostic device (using ANOVA) on cohort of 76 patients divided into 5 groups according to diagnosis and the various level of liver damage.
%K 13C-methacetin
%K dose
%K cumulative dose
%K infrared spectroscopy
%K transmittance
%K absorbance
%K cirrhosis
%U http://versita.metapress.com/content/8201017565267gt0/?p=34e08cefc4b34e6f9ffc885cde1c3a4e&pi=7