%0 Journal Article
%T Serum Concentrations of S100B are not Affected by Cycling to Exhaustion With or Without Vibration
%A Stefanie Schulte
%A Thorsten Schiffer
%A Billy Sperlich
%A Heinz Klein der
%A Hans Christer Holmberg
%J Journal of Human Kinetics
%@ 1899-7562
%D 2011
%I 
%R 10.2478/v10078-011-0073-2
%X The calcium-binding protein S100B is produced primarily by astrocytes and exerts concentration-dependent paracrine and autocrine effects on neurons and glia. The numerous findings of a correlation between S100B and traumatic brain injury (TBI) have resulted in the employment of this protein as a clinical biomarker for such injury. Our present aim was to determine whether cycling with (V) or without (NV) vibration alters serum concentrations of S100B. Twelve healthy, male non-smokers (age: 25.3¡À1.6 yrs, body mass: 74.2¡À5.9 kg, body height: 181.0¡À3.7 cm, VO2peak: 56.9¡À5.1 ml¡¤min-1¡¤kg-1 (means ¡À SD)) completed in random order two separate trials to exhaustion on a vibrating bicycle (amplitude 4 mm and frequency 20 Hz) connected to an ergometer. The initial workload of 100 W was elevated by 50 W every 5 min and the mean maximal period of exercise was 25:27¡À1:30 min. The S100B in venous blood taken at rest, immediately after the test, and 30, 60 and 240 min post-exercise exhibited no significant differences (p>0.05), suggesting that cycling with and without vibration does not influence this parameter.
%K biomarker
%K neurotrophin
%K hormone
%K endurance
%K serum
%U http://versita.metapress.com/content/a55425w225123j70/?p=d987ab92fa004e16ba38bd5695460c8a&pi=6